THE EFFECT OF PASSIVATION ON THE HAEMOCOMPATIBILITY OF 316L STAINLESS STEEL

doi:10.3724/SP.J.1037.2011.00520

Acta Metall Sin

2011, Vol. 47

Issue (12): 1575-1580 DOI: 10.3724/SP.J.1037.2011.00520

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THE EFFECT OF PASSIVATION ON THE HAEMOCOMPATIBILITY OF 316L STAINLESS STEEL

SHI Yongjuan ^1,2, REN Yibin ¹, ZHANG Bingchun ¹, YANG Ke ¹

1. Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016
2. Graduate School of Chinese Academy of Sciences, Beijing 100049

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SHI Yongjuan REN Yibin ZHANG Bingchun YANG Ke. THE EFFECT OF PASSIVATION ON THE HAEMOCOMPATIBILITY OF 316L STAINLESS STEEL. Acta Metall Sin, 2011, 47(12): 1575-1580.

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Abstract The difference of haemocompatibility of medical 316L stainless steel passivated by nitric acid (NT) and citric acid (CT) was studied. Platelet adhesion and protein adsorption were studied to evaluate the haemocompatibility of the 316L stainless steel passivated by the two different methods. XPS analysis, water contact angle and surface charge measurement were used to analyze the surface properties of the steel such as chemical composition and depth distribution of the main elements in passivated films, surface energy and surface charge. The results showed that the 316L steel passivated by citric acid displayed better haemocompatibility, which could be related to the higher surface energy and relatively lower surface charge. The results also showed that the polar component of surface energy was of linear relation with the albumin adsorption on 316L stainless steel while the surface charge had the same relation with fibrinogen adsorption.

Key words: 316L stainless steel passivation platelet adhesion protein adsorption surface energy surface charge

Received: 10 August 2011

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Supported by National Natural Science Foundation of China (No.31000428) and Main Direction Program of Knowledge Innovation of Chinese Academy of Sciences (No.KGCX2–YW–207)

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https://www.ams.org.cn/EN/10.3724/SP.J.1037.2011.00520 OR https://www.ams.org.cn/EN/Y2011/V47/I12/1575

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