Research Status of Biomedical Porous Ti and Its Alloy in China

doi:10.11900/0412.1961.2017.00324

Acta Metall Sin

2017, Vol. 53

Issue (12): 1555-1567 DOI: 10.11900/0412.1961.2017.00324

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Research Status of Biomedical Porous Ti and Its Alloy in China

Erlin ZHANG¹, Xiaoyan WANG², Yong HAN³(

)

1 Key Laboratory for Anisotropy and Texture of Materials, Ministry of Education, School of Materials Science and Engineering, Northeastern University, Shenyang 110819, China
2 School of Metallurgy, Northeastern University, Shenyang 110819, China
3 State Key Laboratory for Mechanical Behavior of Materials, Xi'an Jiaotong University, Xi'an 710049, China

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Erlin ZHANG, Xiaoyan WANG, Yong HAN. Research Status of Biomedical Porous Ti and Its Alloy in China. Acta Metall Sin, 2017, 53(12): 1555-1567.

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Abstract

Porous Ti not only inherits the physical and chemical properties of titanium alloy, such as higher special stiffness, special strength, excellent corrosion resistance and biocompatibility, but also its unique pore structure gives it the characteristic of ultra-low density and large surface area. It is an alternative material for human body with structural and functional integration. It has been widely used in the field of clinical medicien in recent years. Many research and applications show that the properties and functions of porous Ti strongly depend on the pore structure of porous Ti prepared by different methods. Surface activation technology can significantly improve the surface activity of porous Ti and shorten the healing period after implantation. In this paper the common preparation methods of porous Ti were introduced based on the structure and properties of porous Ti. The surface modification, biological activity, osteoinductive properties of porous Ti and their domestic research status were summrized. The development of biomedical porous Ti and titanium alloys was prospected.

Key words: porous Ti titanium alloy corrosion resistance biocompatibility preparation method surface modification

Received: 31 July 2017

ZTFLH:

TG146.23

Fund: Supported by State Key Laboratory for Mechanical Behavior of Materials (No.20151703)

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https://www.ams.org.cn/EN/10.11900/0412.1961.2017.00324 OR https://www.ams.org.cn/EN/Y2017/V53/I12/1555

Table 1 Preparation methods of porous Ti and its alloy^[19,20]

Table 2 Surface modification methods of porous Ti and its alloy^[60]

Table 3 Mechanical properties of autologous bone and bone repair materials^[78,79]

Fig.1 XRD spectra of pure Ti after surface treatment by different methods^[82] (AH—alkali-heat treatment, AC—acid treatment, MAO—micro-arc oxidation)

Fig.2 SEM images of bioactive layer on the Ti surface after heat treatment at 400 ℃ (a~c), 600 ℃ (d~f) and 800 ℃ (g~i) for 0.5 h (a, d, g), 1 h (b, e, h) and 2 h (c, f, i) (surface Ca content is (0.42±0.05)%, atomic fraction)^[83]

Fig.3 Outgrowth of new bone along 0.5% (mass fraction) Si-HA coating outside (fluorescence observation, HA—hydroxyapatite, differences of bone tissue growth are distinguished by red lines in figure)^[83]

Fig.4 Ingrowth of new bone into porous Ti with 0.5%Si-HA coating (fluorescence observation, differences of bone tissue growth are distinguished by red lines in figure)^[83]

Table 4 Absorbance of cultured cells on the surface of porous Ti and HA^[90]

Fig.5 Growth of cells on porous Ti (a) and HA (b)^[90]

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