Research Progress on Biodegradable Zinc-Based Biomaterials
Luning WANG1,2(), Yao MENG1, Lijun LIU1, Chaofang DONG2,3, Yu YAN3
1 School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China 2 State Key Laboratory for Advanced Metals and Materials, University of Science and Technology Beijing, Beijing 100083, China 3 Institute for Advanced Materials and Technology, University of Science and Technology Beijing, Beijing 100083, China
Cite this article:
Luning WANG, Yao MENG, Lijun LIU, Chaofang DONG, Yu YAN. Research Progress on Biodegradable Zinc-Based Biomaterials. Acta Metall Sin, 2017, 53(10): 1317-1322.
In recent years, zinc, as an essential trace element, with its alloys has attracted increasing attention as new biodegradable metals because of its appropriate degradation rate and degradation behavior. In this stage, it appears that the fabrication and degradation mechanism of zinc alloys as biodegradable metal still needs abundant systematic study. This review summarizes progress towards biodegradable zinc alloys. It emphasizes the current understanding of physiological and biological benefits of zinc and its biocompatibility. Finally, the review provides an outlook on challenges in designing zinc-based stents of optimal mechanical properties and biodegradation rate.
Table 1 Key properties and aspects of potential biodegradable metals [11]
Alloy
Phase
State
Ultimate tensile
Elongation
Yield strength
Ref.
strength / MPa
%
MPa
Zn-2Li
Zn, LiZn4
Rolled
370
14.3
245
[21]
Zn-4Li
450
14
425
Zn-6Li
560
2
470
Zn-0.1Li
Zn, LiZn4
Extruded
274±61
17±7
[22]
Zn-4Cu
Zn, CuZn5
Extruded
270±10
51±2
250±10
[23]
Zn-Cu-0.1Mg
Zn, CuZn5, Mg2Zn11
Extruded
380
8
345
[24]
Zn-xAg
Zn, AgZn3
Extruded
203~287
32~39
150~242
[25]
(x=2.5, 5.0, 7.0)
Zn-1Ca
Zn, CaZn13
Rolled
250
13
220
[26]
Zn-1Mg
Zn, MgZn2
Rolled
240
12
190
Zn-1Sr
Zn, SrZn13
Rolled
185
19.6
230
Zn-1Mg-1Ca
Zn, CaZn13, MgZn2
Rolled
197
8.5
138
[27]
Zn-1Mg-1Sr
Zn, SrZn13, MgZn2
Rolled
200
9.5
140
Zn-1Ca-1Sr
Zn, SrZn13, CaZn13
Rolled
202
9
142
Zn-3Mg
Zn, Mg2Zn11
Rolled
104
2.3
[28]
Homogenized
88
8.8
Table 2 Mechanical properties of zinc alloys[21-28]
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