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| PREPARATION AND BIOCOMPATIBILITY OF ZnHA/TiO2 HYBRID COATING |
| ZHANG Jingying1, 2), QI Min3), YANG Dayi3), AI Hongjun1) |
1) School of Stomatology, China Medical University, Shenyang 110001
2) School of Medicine, Dalian University, Dalian 116622
3) School of Materials Science and Engineering, Dalian University of Technology, Dalian 116024 |
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Cite this article:
ZHANG Jingying QI Min YANG Dayi AI Hongjun. PREPARATION AND BIOCOMPATIBILITY OF ZnHA/TiO2 HYBRID COATING. Acta Metall Sin, 2011, 47(4): 429-434.
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Abstract A zinc-containing hydroxyapatite (ZnHA)/titania (TiO2) hybrid coating is developed to improve the mechanical character and biocompatibility of titanium (Ti) implants. The ZnHA layer on Ti via sol-gel method after treated by micro-arc oxidation (MAO) to produce an ZnHA/TiO2 porous titania coating on Ti implants. The chemical composition and physical structure of the modified surface layers were characterized by X-ray photoelectron spectroscopy (XPS) as well as scanning electron microscope (SEM). At the same time, in vitro co-culture assays were performed to evaluate the cell morphology, adhesion and proliferation of MG-63 cells to the modified titanium. The cells micro morphology on the ZnHA/TiO2 coatings were more polygonal compared with round than that on HA/TiO2 coatings by SEM. It was confirmed by Fluorescence microscopy observations that the osteoblast-like cells on the hybrid coating layer adhesion and spread favorably. The results in this work suggest that ZnHA/TiO2 hybrid coatings on Ti substrates can function as an implant with good mechanical character and biocompatibility.
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Received: 06 September 2010
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