可降解锌基生物材料的研究进展

doi:10.11900/0412.1961.2017.00289

金属学报

2017, Vol. 53

Issue (10): 1317-1322 DOI: 10.11900/0412.1961.2017.00289

研究论文

本期目录 | 过刊浏览

可降解锌基生物材料的研究进展

王鲁宁^1,²(

), 孟瑶¹, 刘丽君¹, 董超芳^2,³, 岩雨³

1 北京科技大学材料科学与工程学院北京 100083
2 北京科技大学新金属材料国家重点实验室北京 100083
3 北京科技大学新材料技术研究院北京 100083

Research Progress on Biodegradable Zinc-Based Biomaterials

Luning WANG^1,²(

), Yao MENG¹, Lijun LIU¹, Chaofang DONG^2,³, Yu YAN³

1 School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China
2 State Key Laboratory for Advanced Metals and Materials, University of Science and Technology Beijing, Beijing 100083, China
3 Institute for Advanced Materials and Technology, University of Science and Technology Beijing, Beijing 100083, China

引用本文:

王鲁宁, 孟瑶, 刘丽君, 董超芳, 岩雨. 可降解锌基生物材料的研究进展[J]. 金属学报, 2017, 53(10): 1317-1322.
Luning WANG, Yao MENG, Lijun LIU, Chaofang DONG, Yu YAN. Research Progress on Biodegradable Zinc-Based Biomaterials[J]. Acta Metall Sin, 2017, 53(10): 1317-1322.

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摘要:

Zn作为人体必需的微量元素,具有理论适中的降解速率和降解行为,因此在近年来,成为继镁合金与铁合金后的一种新的可降解医用植入材料。锌合金的设计、加工制备以及降解机理的研究刚处于起步阶段,尚未形成系统性的研究成果。本文就目前可降解锌合金的研究现状及未来的研究方向进行综述。

关键词 ：锌合金, 植入材料, 生物相容性, 降解

Abstract：

In recent years, zinc, as an essential trace element, with its alloys has attracted increasing attention as new biodegradable metals because of its appropriate degradation rate and degradation behavior. In this stage, it appears that the fabrication and degradation mechanism of zinc alloys as biodegradable metal still needs abundant systematic study. This review summarizes progress towards biodegradable zinc alloys. It emphasizes the current understanding of physiological and biological benefits of zinc and its biocompatibility. Finally, the review provides an outlook on challenges in designing zinc-based stents of optimal mechanical properties and biodegradation rate.

Key words： zinc alloy implantation biocompatibility degradation

收稿日期: 2017-07-12

ZTFLH:

TG146.13

基金资助:国家重点研发计划项目No.2016YFC251100

作者简介:

作者简介王鲁宁,男,1980年生,博士,教授

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https://www.ams.org.cn/CN/10.11900/0412.1961.2017.00289 或 https://www.ams.org.cn/CN/Y2017/V53/I10/1317

表1 主要的用于可降解金属支架的材料主要性能[11]

表2 锌合金的力学性能[21-28]

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