MRI磁兼容合金研究

doi:10.11900/0412.1961.2017.00265

金属学报

2017, Vol. 53

Issue (10): 1323-1330 DOI: 10.11900/0412.1961.2017.00265

研究论文

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MRI磁兼容合金研究

任伊宾¹(

), 李俊^1,², 王青川¹, 杨柯¹

1 中国科学院金属研究所沈阳 110016
2 中国科学技术大学材料科学与工程学院沈阳 110016

A Review: Research on MR-Compatible Alloys in MRI

Yibin REN¹(

), Jun LI^1,², Qingchuan WANG¹, Ke YANG¹

1 Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China
2 School of Materials Science and Engineering, University of Science and Technology of China, Shenyang 110016, China

引用本文:

任伊宾, 李俊, 王青川, 杨柯. MRI磁兼容合金研究[J]. 金属学报, 2017, 53(10): 1323-1330.
Yibin REN, Jun LI, Qingchuan WANG, Ke YANG. A Review: Research on MR-Compatible Alloys in MRI[J]. Acta Metall Sin, 2017, 53(10): 1323-1330.

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摘要:

磁共振成像(MRI)是医学领域中不可或缺的影像诊断技术。目前常规使用的金属医疗器械包括植入物在MRI下均会产生较大程度的伪影,影响病理诊断分析。尽管临床上通过技术操作可以减小金属伪影,但伪影仍然无法完全消除。本文综述了目前MRI磁兼容合金的研究进展,包括锆合金、铌合金、铜合金等。与临床应用的医用金属材料相比,本文所述磁兼容合金均能有效降低或消除MRI下的金属伪影。随着MRI诊断技术的普及,可在MRI下精确诊断的生物材料与器械会越来越受到重视,因此开发综合性能优异的磁兼容合金是医用金属材料的发展趋势之一。

关键词 ：磁共振成像, 金属伪影, 磁兼容, 锆合金, 铜合金

Abstract：

Magnetic resonance imaging (MRI) is widely used in clinical applications. Metallic medical devices and implants used under MRI normally produce noticeable artifact which seriously affects image quality. Therefore, the artifact is an essential problem that should be solved for metallic biomaterials. Although artifact can be reduced by technical manipulation, it cannot be eliminated completely. This paper summarizes recent studies on MR-compatible alloys such as Zr alloys, Nb alloys and Cu alloys. Compared with normally clinical metallic materials, MR-compatible alloys described in this article can effectively reduce or eliminate artifacts under MRI. MR-compatibility will become an essential property to implant materials and devices. Thus developing metallic biomaterials with low magnetic susceptibility and excellent comprehensive performance becomes more important.

Key words： magnetic resonance imaging metallic artifact MR-compatibility Zr alloy Cu alloy

收稿日期: 2017-07-03

ZTFLH:

R318.08

基金资助:国家自然科学基金项目No.31370976

作者简介:

作者简介任伊宾,男,1975年生,副研究员,博士

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图1 金属材料的伪影[8]

表1 不同金属材料的体积磁化率[7,12,13]

图2 冷变形量对冷加工态纯Zr与Zr-14Nb合金质量磁化率的影响[17]

图3 铸态Zr-Ru[14]、Zr-Nb[16]、Zr-Mo[18]合金的质量磁化率与合金元素含量的关系

图4 纯Zr、纯Ag、Zr-Ag合金的典型MR伪影图像及三维重建的伪影图像[20]

表2 Nb28Ta3.5W1.3Zr[22]与Nb60Ta2Zr[24]、ABI[27]合金的力学性能

图5 含植入物的兔组织的典型MR图像[21]

图6 10种不同金属在同一条件(主磁场B0=3 T快速自旋回波(FSE))下的三维重建伪影[33]

图7 铜合金支架(箭头)植入猪肾动脉后的伪影表现(B0=1.5 T,使用MR血管造影技术,支架内腔完全无伪影)[31]

图8 纯Cu、硅黄铜和纯Ti的典型MR伪影图像(B0=3.0 T,FSE)[32]

图9 纯Zn在3 T下的伪影表现(FSE,样品平行于B0)

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