Deformation behaviors of [110] and [112] oriented Sn single crystals were investigated under different temperatures and strain rates. It is shown that there are some differences between [110] and [112] orientations. [110] oriented sample has the higher strain rate sensitivity exponent m≈0.133, strain hardening exponent n≈0.54, activation energy Q≈35 kJ/mol and deforms through multiple--slip. While [112] oriented sample has the lower strain rate sensitivity exponent m≈0.108, lower strain hardening exponent n≈0.46, activation energy Q≈52 kJ/mol and deforms through cross-slip and twins together. The first activated slip system is {010}<100>in [110] orientation. The critical-resolved shear stress (CRSS) is 3.1 MPa which is depended on temperature. Deformation process is controlled by the cross--slip according to the activation energy and slip observation.