Maraging steels are leading members of the ultra-high strength steel family due to a combination of two solid state reactions: martensitic transformation and subsequent ageing. These steels can be hardened by the precipitation of refined Ni₃(Ti, Mo) intermetallic particles. They have been widely used in the military and aerospace applications such as solid rocket motor cases and submarine shells due to their high strength and toughness. The T250 maraging steel has used Ti as one of the primary strengthening elements to replace Co, which decreases the cost of maraging steels. Its properties are comparable to the standard Co-bearing grades in the 1.4~2.1 GPa strength levels. It possesses good weldability without porosity in the weld and other weld defects. However, the combination of strength and toughness of welded joints is the main problem which has not been solved well via different welding methods so far. In this work, T250 maraging steel plate with 2 mm thickness was hybrid-treated with laser welding and aging treatment. The strength and toughness of welded joints aged before and after welding were investigated. The microstructures of parent metals and welded joints were observed with OM and SEM. Chemical compositions in parent metals and weld zones were analyzed with EPMA. The tensile strength and static toughness were acquired with the auxiliary device of Gleeble machine and could represent strength and toughness of the welded joints. The results show that the tensile strength and static toughness of the welded joint aged before welding are 62% and 28% that of the aged parent metal, respectively. However, the tensile strength and static toughness of the welded joint aged after welding reach 98% and 71% that of the aged parent metal, respectively. The weld metal is the key zone to influence the strength and toughness of the welded joints. Ni₃(Ti, Mo) precipitates in the weld metal are the intrinsic reason resulting in that the strength and toughness of the welded joint aged after welding are superior to that of the welded joint aged before welding. Ni₃(Ti, Mo) precipitates are beneficial to the strength and static toughness in the elastic deformation stage, and it has a dual effect on the static toughness in the plastic deformation stage of the welded joints. The reverted austenite has a negligible effect on the strength and static toughness in the elastic deformation stage, while it is detrimental to the static toughness in the plastic deformation stage of the welded joints.