A zinc-containing hydroxyapatite (ZnHA)/titania (TiO2) hybrid coating is developed to improve the mechanical character and biocompatibility of titanium (Ti) implants. The ZnHA layer on Ti via sol-gel method after treated by micro-arc oxidation (MAO) to produce an ZnHA/TiO2 porous titania coating on Ti implants. The chemical composition and physical structure of the modified surface layers were characterized by X-ray photoelectron spectroscopy (XPS) as well as scanning electron microscope (SEM). At the same time, in vitro co-culture assays were performed to evaluate the cell morphology, adhesion and proliferation of MG-63 cells to the modified titanium. The cells micro morphology on the ZnHA/TiO2 coatings were more polygonal compared with round than that on HA/TiO2 coatings by SEM. It was confirmed by Fluorescence microscopy observations that the osteoblast-like cells on the hybrid coating layer adhesion and spread favorably. The results in this work suggest that ZnHA/TiO2 hybrid coatings on Ti substrates can function as an implant with good mechanical character and biocompatibility.
ZHANG Jing-Ying
,
ZI Min
,
YANG Tai-Yi
,
YI Hong-Jun
. PREPARATION AND BIOCOMPATIBILITY OF ZnHA/TiO2 HYBRID COATING[J]. Acta Metall Sin, 2011
, 47(4)
: 429
-434
.
DOI: 10.3724/SP.J.1037.2010.00448
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