A novel Fe–30Mn–1C alloy was fabricated by vacuum induction melting, and its mechanical properties, magnetism, degradation behavior in simulated body fluid and in vitro biological properties were studied. The results showed that Fe–30Mn–1C alloy had better mechanical properties than those of Fe–30Mn alloy and 316L stainless steel due to the addition of carbon. Compared with Fe–30Mn, Fe–30Mn–1C alloy showed lower magnetic susceptibility, which is beneficial to the MRI compatibility. Electrochemical impedance spectrum (EIS) results showed that Fe–30Mn–1C alloy had lower polarization resistance, resulting in higher degradation rate compared with Fe–30Mn alloy, which was further confirmed by the static immersion test. The in vitro test results indicated that Fe–30Mn–1C alloy had lower hemolytic ratio, better anticoagulation property and less platelet adhesion as well as good cell compatibility, meeting the basic requirement on medical implants.
XU Wen-Li
,
TAN Li-Li
,
YANG Ke
. STUDY ON PROPERTIES OF A NOVEL BIODEGRADABLE Fe–30Mn–1C ALLOY[J]. Acta Metall Sin, 2011
, 47(10)
: 1342
-1347
.
DOI: 10.3724/SP.J.1037.2011.00258
[1] Liu H Q, Zhang Y, Zhu S F, Weng Y J, Xu L, Huang N. Chin J Interv Imag Ther, 2008; 5: 306
(刘恒全, 张勇, 朱生发, 翁亚军, 徐莉, 黄楠. 中国介入影像与治疗学, 2008; 5: 306)
[2] Waksman R. J Intervent Cardiol, 2006; 19: 414
[3] Di Mario C, Griffiths H, Goktekin O, Peeters N, Verbist J, Bosiers M. J Intervent Cardiol, 2004; 17: 391
[4] Schinhammer M, Hnzi A C, Lffler J F, Uggowitzer P J. Acta Biomater, 2010; 6: 1705
[5] Hermawan H D D, Mantovani D. J Biomed Mater Res, 2010; 93: 1
[6] Zhang E, Chen H, Shen F. J Mater Sci: MaterMed, 2010; 21: 2155
[7] Peuster M, Hesse C, Schloo T, Fink C, Beerbaum P, von Schnakenburg C. Biomaterials, 2006; 27: 4961
[8] Peuster M, Wohlsein P, Brugmann M, Ehlerding M, Seidler K, Fink C. Br Med, 2001; 86: 568
[9] Hermawan H D D, Mantovani D. Adv Mater Res, 2007; 15–17: 107
[10] Mani G, Feldman M D, Patel D, Agrawal C. Biomaterials, 2007; 28: 1689
[11] Umebayashi H, Ishikawa Y. J Phys Soc Jpn, 1968; 39: 1318
[12] Hermawan H, Purnama A, Dube D, Couet J, Mantovani D. Acta Biomater, 2009; 6: 1854
[13] Liu B, Zheng Y F. Mater Lett, 2010; 65: 540
[14] Liu B, Zheng Y F. Acta Biomater, 2011; 7: 1407
[15] Wang L T. Medical Cell Biology. Shenyang: Liaoning Science and Technology Press, 1991: 43
(王兰田. 医学细胞学. 沈阳: 辽宁科学技术出版社, 1991: 43)
[16] Yue L M. Physiology. Beijing: Science Press, 2002: 60
(岳利民. 生理学. 北京: 科学出版社, 2002: 60)
