On Silver Nano Particles and Silver-Bearing Materials as Virus and Bacteria Killing Agents
HU Yemin,LIAN Xintong,DONG Han()
School of Materials Science and Engineering, Shanghai University, Shanghai 200444, China
Cite this article:
HU Yemin,LIAN Xintong,DONG Han. On Silver Nano Particles and Silver-Bearing Materials as Virus and Bacteria Killing Agents. Acta Metall Sin, 2020, 56(4): 633-641.
It is shown by the studies that silver nano particles and silver-bearing materials have noticeable antiviral effects. The research progresses of silver nano particles and silver-bearing materials as antiviral agents are summarized and reviewed based on the aspects of possible antiviral mechanisms as well as bio-safety. The antibacterial effects of Ag-bearing iron and steels, and the effects of Ag on mechanical properties and corrosion resistance, are also summarized. It is shown by the results that silver alloying and silver nano particles could promote the inhabitation of ferrous materials to bacteria and virus.
Fig.1 Schematic of interaction of silver nanoparticles (AgNPs) with virus (e.g. coronavirus)Color online
Fig.2 Immunofluorescence staining analyses of Madin-Darby canine kidney (MDCK) cells in different groups[24] (Extensive specific yellow-green fluorescence indicates cell lesion and death; red indicates normal cell morphology)Color online(a) normal MDCK cells(b) MDCK cells treated with parainfluenza virus type 3 (PIV3) only(c) MDCK cells treated with the mixture of virus and solvent(d) MDCK cells were incubated with 25 mg/L AgNPs for 2 h then infected with PIV3 for a further 2 h(e) treatment of PIV3 with 25 mg/L AgNPs for 2 h prior to incubation with MDCK cells(f) MDCK cells infected with PIV3 for 2 h then incubated with 25 mg/L AgNPs for a further 2 h
Fig.3 Transmission electron microscope negative staining of PIV3[24](a) normal PIV3 (b) PIV3 treated with 150 mg/L AgNPs for 30 min(c) PIV3 treated with 150 mg/L AgNPs for 60 min (d) PIV3 treated with 150 mg/L AgNPs for 120 min
Fig.4 Composition mapping in Ag-bearing gray iron[58](a) OM image of microstructure (b) Ag mapping
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