可降解镁基复合材料的制备及其在骨科领域的研究进展

欧阳思慧, 佘加, 陈先华, 潘复生

Preparation of Biodegradable Mg-Based Composites and Their Recent Advances in Orthopedic Applications

OUYANG Sihui, SHE Jia, CHEN Xianhua, PAN Fusheng

图7 医用镁基材料的体内动物实验[85~93]

Fig.7 In vivo animal experiments of biomedical Mg-based composites (HP represents high-purity; black arrows represent semitendinosus, white arrow represent HP Mg-based screw; BMP-2 represents bone morphogenetic protein-2, VEGF represents vascular endothelial growth factor, GAPDH represents glyceraldehyde-3-phosphate dehydrogenase, BMSCs represent bone marrow mesenchymal stem cells) (a) magnesium-based screw used for tendon-bone interface healing[85] (b) Mg-based interference screw used for tendon fixation[86] (c) Mg-based screw used for fixation of distal femur fracture[87] (d) Mg-based screw and plate system used for ulna fracture fixation[88] (e) Mg-based intramedullary nail used for fixation of femoral shaft fracture[89] (f) Mg-based ring used for anterior cruciate ligament (ACL) reconstruction[90] (g) Mg-based wire promoting meniscus regeneration[91] (h) Mg-based suture anchor and Mg-based wire used for rotator cuff tear repair[92,93]