医用可降解锌合金的生物相容性评价研究进展

王鲁宁, 尹玉霞, 石章智, 韩倩倩

Research Progress on Biocompatibility Evaluation of Biomedical Degradable Zinc Alloys

WANG Luning, YIN Yuxia, SHI Zhangzhi, HAN Qianqian

表2 锌合金主要降解产物的性质

Table 2 Properties of the main degradation products of Zn alloys

Degradation Solubility, 20oC Stability Density LD50, acute systemic Equivalent to human Toxicity product g·L-1 g·cm-3 toxicity, oral, rat lethal dose level mg·kg-1 g ZnO 0.0029, Stable 5.68 > 2000 50 Low toxicity slightly soluble ZnCO3·3Zn(OH)2 Insoluble Stable - > 10000 500 Non-toxic Zn3(PO4)2 2.7, Stable - > 5000 500 Non-toxic slightly soluble ZnCl2 Soluble Stable 1.01 > 5000 500 Non-toxic