蛋白质吸附对医用金属材料体外腐蚀行为的影响
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王鲁宁, 刘丽君, 岩雨, 杨坤, 陆黎立
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Influences of Protein Adsorption on the in vitro Corrosion of Biomedical Metals
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WANG Luning, LIU Lijun, YAN Yu, YANG Kun, LU Lili
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表2 血浆、关节滑液、几种常用模拟体液和模拟血浆的主要化学成分[3,10~15]
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Table 2 Chemical components of blood plasma, synovia fluids, several commonly used simulated body fluids and simulated blood plasma[3,10-15]
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| Fluid | Na+ | K+ | Ca2+ | Mg2+ | Cl- | HCO-3 | HPO2-4 | H2PO-4 | SO2-4 |
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| mmol·L-1 | mmol·L-1 | mmol·L-1 | mmol·L-1 | mmol·L-1 | mmol·L-1 | mmol·L-1 | mmol·L-1 | mmol·L-1 | | Blood plasma[10,13] | 134-143 | 3.5-4.7 | 2.1-2.7 | 1.5 | 100-108 | 25-30 | 1.0 | - | 0.5 | | Synovia fluids[10] | 133-139 | 3.5-4.5 | 1.2-2.4 | | 87-138 | - | - | - | | | SBF[15] | 142.0 | 5.0 | 2.5 | 1.5 | 148.0 | 4.2 | 1.0 | - | 0.5 | | PBS[3] | 154.1 | 4.1 | - | - | 140.6 | - | 8.1 | 1.5 | - | | HBSS[3,12] | 142.8 | 5.8 | 2.5 | 0.8 | 143.3 | 4.2 | 0.3 | 0.4 | 0.8 | | DMEM[3,12] | 155.3 | 5.3 | 1.8 | 0.8 | 115.7 | 44.1 | 0.9 | - | 0.8 | | Ringer??s[14] | 147 | 4.1 | 4.3 | - | 160 | - | - | - | - | | SBP[11] | 142.0 | 5.0 | 2.5 | 1.5 | 103.0 | 27.0 | 1.0 | - | 0.5 | | Fluid | Amino acids | Glucose | Uric acid | Vitamins | Phenol red | Albumin | IgG | Fibrinogen | | g·L-1 | g·L-1 | g·L-1 | | | g·L-1 | g·L-1 | g·L-1 | | Blood plasma[10,13] | 20-51 | 650-966 | 30.5-70.7 | - | - | 37.6-54.9 | 6.4-13.5 | 2-4 | | Synovia fluids[10] | - | - | 39 | - | | 6-10 | 1.47-4.62 | - | | SBF[15] | - | - | | - | - | | | | | PBS[3] | - | - | | - | - | | | | | HBSS[3,12] | - | 5.6 | | - | - | | | | | DMEM[3,12] | 10.6 | 25.0 | | 0.15 | 0.04 | | | | | Ringer??s[14] | - | - | | - | - | | | | | SBP[11] | - | - | | - | - | | | |
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