蛋白质吸附对医用金属材料体外腐蚀行为的影响

王鲁宁, 刘丽君, 岩雨, 杨坤, 陆黎立

Influences of Protein Adsorption on the in vitro Corrosion of Biomedical Metals

WANG Luning, LIU Lijun, YAN Yu, YANG Kun, LU Lili

表1 Mg及镁合金体内外测试中的腐蚀速率^[3~7] (mm/a, unless otherwise indicated)

Table 1 The in vitro and in vivo corrosion rates of Mg and Mg alloys^[3-7]

Material	In vitro			In vivo	Ref.
Material	In vitro			In vivo
	Solution	Weight loss	Hydrogen evolution	Volume reductions/
	Solution	Weight loss	Hydrogen evolution	Volume reductions/
				weight loss
Pure Mg	PBS	0.28±0.07	0.19±0.02	0.15±0.03	[3]
	HBSS	0.72±0.31	0.57±0.07
	DMEM	1.07±0.10	0.57±0.07
Mg-10Gd	PBS	0.61±0.10	0.40±0.10	1.11±0.05	[3]
	HBSS	1.57±0.62	1.23±0.56
	DMEM	0.42±0.12	0.20±0.01
Mg-2Ag	PBS	16.71±3.06	15.12±2.97	0.13±0.04	[3]
	HBSS	5.41±0.71	3.48±0.36
	DMEM	2.21±0.26	0.68±0.04
Pure Mg	DMEM	Static immersion 1.6±0.3 Aortic bioreactor: Lumen>4.0±0.8 Wall 1.9±0.5		Aortic lumen 1.1±0.3	[4]
				Aortic wall 1.5±0.6


Mg-2Sr	HBSS	~0.37	~0.32	1.37	[5]
Mg-2Sr-Ca	HBSS	~0.24	~0.21	1.10	[5]
Mg-2Sr-Zn	HBSS	~0.15	~0.11	0.85	[5]
Pure Mg	HBSS	17.2%±0.5% (14 d)		65.4%±1.5% (4 weeks)	[6]
Mg+Ca-Sr-P coating	HBSS	4.8%±0.7% (14 d)		76.7%±1.9% (4 weeks)	[6]
Mg-30%Sc (mass fraction)	HBSS		α+β phase 3.4±0.1	β phase 0.06±0.01	[7]
			Single phase 2.9±0.1